Appscript is a high-level, user-friendly Apple event bridge that allows you to control scriptable Mac OS X applications from Python, Ruby and Objective-C. Appscript makes these languages serious alternatives to Apple's own AppleScript language for automating your Mac.
For example, to get the value of the first paragraph of the topmost document in TextEdit using appscript:
This is equivalent to the AppleScript statement:
tell application "TextEdit" get paragraph 1 of document "Read Me" end tell
To find out more about each version of appscript: